Is it Possible to Experience Melatonin Overdose?

24 December 2023 2781
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Melatonin, while being a natural hormone in the body, is often used in supplement forms like tablets or gummies to promote sleep. This may lead you to wonder if it's possible to overdose on melatonin gummies. In brief, yes, you can overdose on melatonin, and symptoms can include excessive sleepiness and restlessness.

Overdosing on melatonin is not just confined to adults; even infants as young as one or two can be affected. However, the topic of melatonin overdose still needs further research, so here are some other things you need to know about melatonin and the potential risks it carries, including overdoses.

The body naturally produces melatonin which regulates our sleep-wake cycle. It's also available for purchase over the counter as a sleeping aid for both adults and children in various forms, such as tablets, capsules, liquids, and gummies.

The safe dosage for melatonin varies, but adults typically take up to 8 milligrams (mg). This dosage is generally safe for short-term use, typically up to six months.

Despite its overall non-toxic nature, melatonin overdose can occur regardless of age, even if you consume a large quantity.

The symptoms of a melatonin overdose can resemble those of typical melatonin usage. These include:

A CDC study on melatonin ingestion in children showed that while most melatonin-ingesting children (82.8%) didn't exhibit symptoms, those who did, typically experienced issues with their gastrointestinal, cardiovascular, or central nervous systems. Alarmingly, 1.6% of these children—4,555 in number—had more severe reactions. In particular, five children needed mechanical ventilation, and two children passed away from overdosing.

There's no direct treatment for a melatonin overdose other than providing supportive care. One common suggestion is for a responsible adult to supervise the person who has taken excessive melatonin, ensuring they wake up rejuvenated.

The aforementioned CDC study also stated that the 27,795 children who showcased symptoms were treated at a healthcare facility. While the majority were discharged shortly after, 14.7% required additional hospitalization, and 1% needed critical care.

Adults can safely consume melatonin for short periods, and potentially even long periods. However, FDA regulations on dietary supplements are minimal and they are not appropriate for everyone. Those with particular health conditions or statuses should avoid melatonin use.

Furthermore, the effect of the supplement's efficacy can vary depending on the form, dosage, frequency of use, and interactions with other medications. Always consult a healthcare provider or pharmacist before starting, including melatonin.

Melatonin usage, while generally safe, can potentially pose dangers beyond an overdose. It may interact with other medications and supplements. Another pressing issue is the lack of regulation on the vitamins and supplements industry. This can mean certain products may have more or a different ingredient than advertised. Some melatonin supplements may contain 83%-478% more melatonin than listed on the label, especially in chewable melatonin formulations.

A normal dosage for children is up to 3mg of melatonin for up to three months. If your child requires a higher dosage, always consult and coordinate with a pediatrician before administering any medications or supplements.

Melatonin poisoning can be prevented by following the instructions on the packaging and consulting a healthcare provider on its suitability and dosage. Ensure all drugs and supplements, including melatonin, are kept out of children's reach. If they aren't packaged in child-resistant containers, transfer them into more secure packaging.

A melatonin overdose can occur if too much is consumed, resulting in symptoms such as sleepiness, headaches, and nausea. No specific treatments exist for melatonin overdose, but supportive care can help. Always discuss with a healthcare provider before utilizing these supplements, as they may not be suitable for everyone.


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